The first verse of the song evokes an image of a club, dark, like a jungle. People are amazed and confused, similar to the Earth's state now.

In the second verse, this image is further developed, with the names of worldly, sometimes sinful things, like bullets, and gold. Bono sings, "I can't stand the beats, I'm asking for the cheque, the girl with crimson nails has Jesus round her neck." He doesn't want to be in this place or this state of vertigo (dizziness) accompanying it. He sees a girl with a rosary/Jesus necklace around her neck and he's completely absorbed in it.

Then in the bridge, the lyrics are a paraphrasing of scripture, where Satan tempts Jesus: "All of this can be yours. Just give me what I want and no one gets hurt." This symbolizes temptation that people face, specifically, Bono, or the main character in this song, while in the club. Then after a sudden and brief rest, which I guess is to symbolize a peak of temptation, the chorus kicks in, showing that Bono, or the main character has chosen not to give in to this temptation.

The chorus also shows some meaning: "Hello, Hello (Hola!)/ We're at a place called Vertigo (Donde esta? [Or "como estas?" or "Bogota" depending on what you think]) It's everything I wish I didn't know (or "Lights go down and all I know") But you give me something, I can feel you love teaching me how..your love is teaching me how...how to kneel..kneel..." He doesn't want to be in temptation, and God is helping him through it.

That's about it. Also, something interesting I saw: If you watch the video, the rings rising around the band seem to grow as the song goes on and then after the bridge don't seem to rise much after that. If you look at this song as being about temptation, the rings could symbolize the temptation I was talking about.